How to Launch a Mental Health Newsletter on Substack in 2025
The mental health conversation has never been more urgent — or more mainstream. In a post-pandemic, hyper-digital, burnout-prone world, readers are actively seeking content that helps them manage anxiety, build resilience, and prioritize their mental well-being. A newsletter on mental health is not only relevant — it’s essential.
This week, we’re diving into how to launch a high-value mental health newsletter on Substack in 2025. You'll learn:
Why this theme remains both evergreen and culturally vital
Who your readers are and what they’re really looking for
How to structure, grow, and monetize your newsletter strategically
Real-world examples of successful Substack creators in this space
This article is for: therapists, coaches, curators, researchers, and solo creators passionate about psychology, well-being, or burnout recovery — and ready to build a newsletter with impact.
If you’re serious about building a high-performing newsletter in 2025, I’ve explored 55 strategic Substack niches in my book Newsletter Empire. It’s a compact, actionable playbook for creators who want clarity and momentum. Check the description on Amazon for a full overview of what’s inside.
🔍 1. Theme
Mental Health
Mental health is no longer a niche topic. From Gen Z to Boomers, awareness and demand for tools to cope with emotional distress, burnout, and social isolation have surged. Over the last five years, Google Trends has shown a steady rise in queries like “how to manage anxiety” and “burnout recovery.” On Substack, categories like psychology, wellness, and self-care are among the most followed.
The opportunity? Mental health content that is grounded, digestible, and non-performative. There’s space for both clinical insight and lived experience. A newsletter can deliver this in a format that feels more human than an app — and more trustworthy than algorithmic TikTok advice.
🎯 2. Target Audience
Mental health newsletters attract: